Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
| ▸ | ILK | Q13418 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8142194 | 0.81 | CYP1A2 (0.46) | MAPTLMNAMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL8126380 | 0.80 | CYP1A2 (0.51) | MAPTLMNAMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL3231476 | 0.80 | MAPT (0.61) | MAPTLMNAMAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL28543158 | 0.79 | SMN1; SMN2 (0.53) | MAPTLMNAMAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL23337477 | 0.79 | ACVRL1 (0.55) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8124072 | 0.78 | GABRA2 (0.50) | MAPTLMNAMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL15561934 | 0.77 | GABRA1 (0.43) | MAPTLMNAMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL15561935 | 0.77 | GABRA1 (0.43) | MAPTLMNAMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL7868789 | 0.77 | AR (0.48) | SMN1; SMN2NPC1RAB9AHPGDKMT2A | |
| SCHEMBL7107744 | 0.77 | CDC25B (0.69) | MAPTLMNAMAPK1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111925357-B | Acylhydrazone compound, pharmaceutical composition and application thereof | 中国科学院昆明植物研究所 | 2023-06-06 | — | — | CN | disclosed |
| CN-111925357-A | Acylhydrazone compound, pharmaceutical composition and application thereof | 中国科学院昆明植物研究所 | 2020-11-13 | — | — | CN | disclosed |