Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.37 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.35 |
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3767200 | 0.80 | IDO1 (0.51) | SGMS2 | |
| SCHEMBL7024874 | 0.78 | IDO1 (0.53) | ALOX5APFEN1SGMS2SLC6A4 | |
| SCHEMBL5541550 | 0.77 | OPRM1 (0.44) | ALOX5APFEN1SGMS1SGMS2HDAC3 | |
| SCHEMBL2452025 | 0.76 | MRGPRX4 (0.41) | RXRARXRBRXRGGRIN2BSLC6A4 | |
| SCHEMBL2088385 | 0.76 | RXRA (0.35) | RXRARXRBRXRGSLC6A3SLC6A2 | |
| SCHEMBL3326060 | 0.76 | IDO1 (0.48) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL80520 | 0.74 | KIF11 (0.31) | — | |
| SCHEMBL9061838 | 0.73 | EPHX2 (0.46) | ALOX5APFEN1SGMS1SGMS2HDAC3 | |
| SCHEMBL28555601 | 0.72 | MAOB (0.45) | ALOX5APFEN1SLC6A4CETP | |
| SCHEMBL2721265 | 0.72 | IDO1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108329330-B | 2-benzyloxy phenyl oxazolopyridine compound and pharmaceutical application thereof | 复旦大学 | 2021-05-04 | — | — | CN | disclosed |