Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | AKT1 | P31749 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3310563 | 0.85 | NFE2L2 (0.53) | NFE2L2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL2232370 | 0.85 | NFE2L2 (0.53) | NFE2L2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL2232374 | 0.85 | NFE2L2 (0.53) | NFE2L2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL6502837 | 0.83 | MAPT (0.53) | NFE2L2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL6502839 | 0.83 | MAPT (0.53) | NFE2L2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL4732473 | 0.83 | NFE2L2 (0.52) | NFE2L2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL28539743 | 0.81 | CYP1A2 (0.63) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL28547583 | 0.81 | GAA (0.48) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL280061 | 0.79 | NFE2L2 (0.61) | NFE2L2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL28541054 | 0.79 | ALDH1A1 (0.51) | MEN1KMT2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108912142-B | Pyrrolobenzooxazinone compound, injection thereof and application thereof in antithrombotic | 延边大学 | 2021-06-18 | — | — | CN | disclosed |
| CN-108276287-B | Synthesis method of 4-oxo acrylate derivative catalyzed by visible light | 浙江工业大学 | 2021-04-06 | — | — | CN | disclosed |