Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | AKT1 | P31749 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502837 | 1.00 | MAPT (0.53) | MAPTRAB9ANPC1SMN1; SMN2NFE2L2 | |
| SCHEMBL2232370 | 0.83 | NFE2L2 (0.53) | MAPTRAB9ANPC1SMN1; SMN2NFE2L2 | |
| SCHEMBL28546110 | 0.83 | NFE2L2 (0.53) | MAPTRAB9ANPC1SMN1; SMN2NFE2L2 | |
| SCHEMBL3310563 | 0.83 | NFE2L2 (0.53) | MAPTRAB9ANPC1SMN1; SMN2NFE2L2 | |
| SCHEMBL2232374 | 0.83 | NFE2L2 (0.53) | MAPTRAB9ANPC1SMN1; SMN2NFE2L2 | |
| SCHEMBL28760212 | 0.82 | MEN1 (0.49) | MAPTRAB9ANPC1SMN1; SMN2NFE2L2 | |
| SCHEMBL4732473 | 0.81 | NFE2L2 (0.52) | MAPTRAB9ANPC1SMN1; SMN2NFE2L2 | |
| SCHEMBL9873850 | 0.81 | ALDH1A1 (0.53) | MAPTRAB9ANPC1SMN1; SMN2NFE2L2 | |
| SCHEMBL2791186 | 0.80 | NFE2L2 (0.59) | MAPTRAB9ANPC1SMN1; SMN2NFE2L2 | |
| SCHEMBL8104632 | 0.80 | NFE2L2 (0.59) | MAPTRAB9ANPC1SMN1; SMN2NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005035497-A1 | CASPASE INHIBITOR COMPRISING 2-ALKYL-4-OXOBUTANOYL GROUP AND PHARMACEUTICAL COMPOSITION THEREOF | LG LIFE SCIENCES LTD. (KR) | 2005-04-21 | — | — | WO | disclosed |
| US-20030032736-A1 | Acrylic adhesive compositions containing ketonyl (meth)acrylate | KNEAFSEY BRENDAN J (IE) | 2003-02-13 | — | — | US | disclosed |
| WO-2001051576-A1 | ACRYLIC ADHESIVE COMPOSITIONS CONTAINING KETONYL (METH)ACRYLATE | LOCTITE (R & D) LIMITED (IE) | 2001-07-19 | — | — | WO | disclosed |