Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | GPR6 | P46095 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853091 | 0.90 | MAPT (0.49) | CCR1MAPTKDM4EALDH1A1POLB | |
| SCHEMBL2858033 | 0.81 | KDM4E (0.58) | CCR1MAPTKDM4EALDH1A1POLB | |
| SCHEMBL2856075 | 0.81 | NAMPT (0.56) | MAPTKDM4EALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL2852992 | 0.80 | CCR1 (0.53) | CCR1MAPTKDM4EALDH1A1POLB | |
| SCHEMBL2855462 | 0.79 | MAPT (0.54) | CCR1MAPTKDM4EALDH1A1POLB | |
| SCHEMBL2856202 | 0.78 | CCR1 (0.55) | CCR1MAPTKDM4EALDH1A1POLB | |
| SCHEMBL2852931 | 0.77 | KDM4E (0.57) | CCR1MAPTKDM4EALDH1A1POLB | |
| SCHEMBL2854457 | 0.77 | CYP3A4 (0.43) | MAPTPOLBSMN1; SMN2CYP3A4KMT2A | |
| SCHEMBL2860428 | 0.76 | KDM4E (0.52) | CCR1MAPTKDM4EALDH1A1POLB | |
| SCHEMBL2855128 | 0.76 | TRPC3 (0.56) | CCR1MAPTKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |