Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28538276 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1ALDH1A1RAB9AKDM4E | |
| SCHEMBL28548203 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2NPC1ALDH1A1RAB9AKDM4E | |
| SCHEMBL28532820 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1ALDH1A1RAB9AKDM4E | |
| SCHEMBL28537622 | 0.84 | ADORA3 (0.40) | SMN1; SMN2NPC1ALDH1A1RAB9AKDM4E | |
| SCHEMBL28537620 | 0.81 | NPC1 (0.42) | SMN1; SMN2NPC1ALDH1A1RAB9AKDM4E | |
| SCHEMBL28910782 | 0.79 | NPC1 (0.38) | SMN1; SMN2NPC1ALDH1A1RAB9AKDM4E | |
| SCHEMBL10426454 | 0.71 | GCGR (0.44) | SMN1; SMN2NPC1ALDH1A1RAB9AKDM4E | |
| SCHEMBL23843785 | 0.70 | NR3C1 (0.54) | SMN1; SMN2NPC1ALDH1A1RAB9AKDM4E | |
| SCHEMBL3219844 | 0.69 | ALDH1A1 (0.43) | SMN1; SMN2NPC1ALDH1A1RAB9AKDM4E | |
| SCHEMBL18012440 | 0.69 | ALDH1A1 (0.44) | SMN1; SMN2NPC1ALDH1A1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109810112-B | Preparation method of indolo [2,1-a ] phthalazine derivative | 华侨大学 | 2021-03-23 | — | — | CN | disclosed |