SCHEMBL28546281

SCHEMBL28546281

CC(=O)NC(C)(C(=O)O)c1cccc2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.45
ALDH1A1 P00352 2/20 0.45
HSD17B10 Q99714 1/20 0.45
ACP3 P15309 1/20 0.42
MTNR1A P48039 2/20 0.41
MTNR1B P49286 2/20 0.41
SSTR4 P31391 3/20 0.41
ABCC9 O60706 1/20 0.40
ABCC8 Q09428 1/20 0.40
KCNJ11 Q14654 1/20 0.40
KCNJ8 Q15842 1/20 0.40
CA12 O43570 1/20 0.40
CA4 P22748 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
PPARG P37231 2/20 0.40
PPARA Q07869 2/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27702983 1.00 KDM4E (0.45) KDM4EALDH1A1HSD17B10ACP3MTNR1A
SCHEMBL1471745 1.00 KDM4E (0.45) KDM4EALDH1A1HSD17B10ACP3MTNR1A
SCHEMBL3004207 0.85 ALDH1A1 (0.48) KDM4EALDH1A1HSD17B10ACP3SSTR4
SCHEMBL1748476 0.85 ALDH1A1 (0.48) KDM4EALDH1A1HSD17B10ACP3SSTR4
SCHEMBL6375660 0.85 ALDH1A1 (0.48) KDM4EALDH1A1HSD17B10ACP3SSTR4
SCHEMBL3390209 0.85 MAPT (0.43) KDM4EALDH1A1HSD17B10ACP3MTNR1A
SCHEMBL1878848 0.84 KDM4E (0.47) KDM4EALDH1A1HSD17B10ACP3SSTR4
SCHEMBL27507947 0.84 KDM4E (0.47) KDM4EALDH1A1HSD17B10ACP3SSTR4
SCHEMBL660493 0.84 KDM4E (0.47) KDM4EALDH1A1HSD17B10ACP3SSTR4
SCHEMBL27479791 0.80 KDM4E (0.44) KDM4EALDH1A1HSD17B10ACP3MTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108752232-B Synthetic method of alpha-quaternary carbon amino acid 四川大学 2021-03-19 CN disclosed