Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKN1 | Q16512 | 1/20 | 0.48 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11867640 | 0.83 | HPGD (0.49) | PKN1PKN2LMNAHPGDTP53 | |
| SCHEMBL4926544 | 0.80 | BRD4 (0.46) | RAB9ALMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL10865148 | 0.79 | SMN1; SMN2 (0.49) | RAB9ALMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL12091648 | 0.78 | PKN1 (0.51) | PKN1PKN2RAB9ALMNASMN1; SMN2 | |
| SCHEMBL10592159 | 0.76 | CCR2 (0.52) | RAB9ALMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL11389479 | 0.75 | HRH1 (0.47) | LMNATSHRSMN1; SMN2HPGDCNR1 | |
| SCHEMBL11388562 | 0.75 | HPGD (0.45) | LMNAHTTSMN1; SMN2HPGDCNR1 | |
| SCHEMBL11390451 | 0.74 | MAPT (0.51) | LMNAHPGDTP53MAPT | |
| Hydrochloric Acid SCHEMBL11868987 | 0.74 | HRH1 (0.46) | LMNATSHRSMN1; SMN2HPGDCNR1 | |
| Hydrochloric Acid SCHEMBL11871667 | 0.73 | MAPT (0.50) | LMNASMN1; SMN2HPGDTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107496419-B | Cyclopenta [ b ] pyrrole compound with anti-inflammatory activity | 兰州大学 | 2021-03-23 | — | — | CN | disclosed |