SCHEMBL2295522

SCHEMBL2295522

Brc1cc(-n2ccc3cccnc32)cc(-n2ccc3cccnc32)c1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CDC7 O00311 1/20 0.49
CDK2 P24941 1/20 0.49
SLC22A12 Q96S37 7/20 0.43
PARP1 P09874 1/20 0.41
CYP2C19 P33261 2/20 0.40
CYP1A2 P05177 1/20 0.40
HTT P42858 1/20 0.40
BRAF P15056 2/20 0.39
RAPGEF4 Q8WZA2 1/20 0.38
SLC22A6 Q4U2R8 1/20 0.37
ABCG2 Q9UNQ0 1/20 0.37
PKM P14618 1/20 0.36
MKNK2 Q9HBH9 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2295440 0.91 CDC7 (0.56) CDC7CDK2SLC22A12PARP1CYP2C19
SCHEMBL28547121 0.85 CDC7 (0.50) CDC7CDK2SLC22A12PARP1CYP2C19
SCHEMBL2294384 0.84 CDC7 (0.53) CDC7CDK2SLC22A12PARP1CYP2C19
SCHEMBL16863761 0.80 RAPGEF4 (0.50) CDC7CDK2SLC22A12PARP1CYP2C19
SCHEMBL30828406 0.79 CDC7 (0.54) CDC7CDK2SLC22A12PARP1CYP2C19
SCHEMBL1150333 0.79 CDC7 (0.54) CDC7CDK2SLC22A12PARP1CYP2C19
SCHEMBL2295195 0.77 CDC7 (0.53) CDC7CDK2SLC22A12PARP1CYP2C19
SCHEMBL13204200 0.77 MKNK2 (0.52) CDC7CDK2SLC22A12PARP1CYP2C19
SCHEMBL415753 0.76 CDC7 (0.51) CDC7CDK2SLC22A12PARP1CYP2C19
SCHEMBL30405693 0.76 CDC7 (0.51) CDC7CDK2SLC22A12PARP1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7989089-B2 2-(9-anthryl)imidazo[4,5-f]-[1,10]phenanthroline (2) or 2-(2-pyridyl)imidazo[4,5-f]-[1,10]phenanthroline (4) LG DISPLAY CO., LTD. (KR) 2011-08-02 US disclosed
US-20060036114-A1 Organoboron luminescent compounds and methods of making and using same QUEEN'S UNIVERSITY AT KINGSTON (CA) 2006-02-16 US disclosed
US-20040265629-A1 Organic luminescent compounds and methods of making and using same QUEEN'S UNIVERSITY AT KINGSTON (CA) 2004-12-30 US disclosed
US-20040265628-A1 Organic luminescent compounds and methods of making and using same LG DISPLAY CO., LTD. (KP) 2004-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060036114-A1 Organoboron luminescent compounds and methods of making and using same SLC43A1, SLC1A5, SLC9B2 CDC7 3636/4885CDK2 4097/4885SLC22A12 32/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.