Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29078290 | 0.99 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2GAAKDM4EMAPT | |
| SCHEMBL28386256 | 0.88 | TRPV1 (0.42) | ALDH1A1SMN1; SMN2GAAKDM4EMAPT | |
| SCHEMBL22978732 | 0.78 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2GAAKDM4EMAPT | |
| SCHEMBL29100724 | 0.76 | MAPK1 (0.39) | ALDH1A1SMN1; SMN2KDM4EMAPTHSD17B10 | |
| SCHEMBL12775512 | 0.75 | POLB (0.50) | ALDH1A1SMN1; SMN2KDM4EHSD17B10KMT2A | |
| SCHEMBL26111081 | 0.75 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2GAAKDM4EMAPT | |
| SCHEMBL18297996 | 0.75 | SMN1; SMN2 (0.76) | ALDH1A1SMN1; SMN2GAAMAPTMEN1 | |
| SCHEMBL4230139 | 0.74 | THRB (0.43) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL29057627 | 0.72 | ELANE (0.40) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL28324227 | 0.71 | SMN1; SMN2 (0.65) | ALDH1A1SMN1; SMN2GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112334451-A | Heterocyclic compounds as kinase inhibitors | 诺维逊生物股份有限公司 | 2021-02-05 | — | — | CN | disclosed |