Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31246118 | 0.86 | HTR1A (0.43) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL23851238 | 0.86 | HTR1A (0.43) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL29078290 | 0.80 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL16835454 | 0.79 | SMN1; SMN2 (0.63) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL28547792 | 0.78 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL26111081 | 0.75 | ALDH1A1 (0.59) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL18297996 | 0.75 | SMN1; SMN2 (0.76) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6523680 | 0.74 | PLAU (0.46) | ALDH1A1KDM4EMAPTSMN1; SMN2GAA | |
| SCHEMBL30986044 | 0.74 | PKM (0.60) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL20615643 | 0.74 | KDM4E (0.50) | ALDH1A1KDM4EKMT2AGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021026803-A1 | PIPERIDINYL-METHYL-PURINEAMINES AS NSD2 INHIBITORS AND ANTI-CANCER AGENTS | NOVARTIS AG (CH) | 2021-02-18 | — | — | WO | disclosed |