SCHEMBL28547906

SCHEMBL28547906

O=[N+]([O-])c1ccc(S(=O)(=O)N2CC2c2cccc(Cl)c2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.58
MMP2 P08253 2/20 0.51
RAB9A P51151 1/20 0.50
KMT2A Q03164 1/20 0.50
RECQL P46063 1/20 0.46
TDP1 Q9NUW8 2/20 0.44
FAAH O00519 1/20 0.44
TERT O14746 1/20 0.43
PARL Q9H300 1/20 0.42
MMP1 P03956 1/20 0.41
MMP7 P09237 1/20 0.41
MMP9 P14780 1/20 0.41
MMP12 P39900 1/20 0.41
MMP14 P50281 1/20 0.41
MMP15 P51511 1/20 0.41
MMP16 P51512 1/20 0.41
MMP26 Q9NRE1 1/20 0.41
ACHE P22303 1/20 0.41
MAPT P10636 3/20 0.41
PSEN1 P49768 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29620268 1.00 ALDH1A1 (0.58) ALDH1A1MMP2RAB9AKMT2ARECQL
SCHEMBL1792211 0.85 ALDH1A1 (0.50) ALDH1A1MMP2RAB9AKMT2APARL
SCHEMBL1571372 0.84 ALDH1A1 (0.68) ALDH1A1MMP2RAB9AKMT2AFAAH
SCHEMBL31173291 0.84 ALDH1A1 (0.71) ALDH1A1MMP2RAB9AKMT2ATDP1
SCHEMBL1792200 0.84 ALDH1A1 (0.71) ALDH1A1MMP2RAB9AKMT2ATDP1
SCHEMBL17970868 0.83 ALDH1A1 (0.62) ALDH1A1MMP2RAB9AKMT2APSEN1
SCHEMBL17961617 0.83 ALDH1A1 (0.62) ALDH1A1MMP2RAB9AKMT2APSEN1
SCHEMBL1789530 0.80 KMT2A (0.58) ALDH1A1MMP2RAB9AKMT2ATDP1
SCHEMBL4298802 0.77 MMP2 (0.46) ALDH1A1MMP2KMT2ARECQLTDP1
SCHEMBL4298798 0.77 MMP2 (0.46) ALDH1A1MMP2KMT2ARECQLTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112608269-B Method for catalytically synthesizing pyrrolidine by weak interaction of chalcogen 山东大学 2022-05-06 CN disclosed
CN-112608269-A Method for catalytically synthesizing pyrrolidine by weak interaction of chalcogen 山东大学 2021-04-06 CN disclosed