Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | PARL | Q9H300 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 4/20 | 0.45 |
| ▸ | MMP3 | P08254 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1790581 | 0.86 | MAPT (0.58) | ALDH1A1KMT2ARAB9AMMP2PARL | |
| SCHEMBL1792783 | 0.86 | MAPT (0.58) | ALDH1A1KMT2ARAB9AMMP2PARL | |
| SCHEMBL12614112 | 0.86 | TRPA1 (0.55) | ALDH1A1KMT2ARAB9AMMP2PARL | |
| SCHEMBL27981545 | 0.86 | MAPT (0.58) | ALDH1A1KMT2ARAB9AMMP2PARL | |
| SCHEMBL1792200 | 0.86 | ALDH1A1 (0.71) | ALDH1A1KMT2ARAB9APSEN1PSEN2 | |
| SCHEMBL31173291 | 0.86 | ALDH1A1 (0.71) | ALDH1A1KMT2ARAB9APSEN1PSEN2 | |
| SCHEMBL29620268 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KMT2ARAB9APSEN1PSEN2 | |
| SCHEMBL28547906 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KMT2ARAB9APSEN1PSEN2 | |
| SCHEMBL12614703 | 0.83 | ALDH1A1 (0.48) | ALDH1A1KMT2ARAB9AMMP2PARL | |
| SCHEMBL1793733 | 0.83 | HSD11B1 (0.61) | ALDH1A1KMT2ARAB9AMMP2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112608269-B | Method for catalytically synthesizing pyrrolidine by weak interaction of chalcogen | 山东大学 | 2022-05-06 | — | — | CN | disclosed |
| CN-112608269-A | Method for catalytically synthesizing pyrrolidine by weak interaction of chalcogen | 山东大学 | 2021-04-06 | — | — | CN | disclosed |
| EP-3144303-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | Array Biopharma, Inc. (US) | 2017-03-22 | — | — | EP | disclosed |
| US-9556139-B2 | 6-substituted phenoxychroman carboxylic acid derivatives | ARRAY BIOPHARMA INC. (US) | 2017-01-31 | — | — | US | disclosed |
| EP-2826774-B1 | Intermediates for 6-substituted phenoxychroman carboxylic acid derivatives | ARRAY BIOPHARMA INC (US) | 2016-05-25 | — | — | EP | disclosed |
| US-20150232442-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | ARRAY BIOPHARMA INC. (US) | 2015-08-20 | — | — | US | disclosed |
| US-9096567-B2 | 6-substituted phenoxychroman carboxylic acid derivatives | ARRAY BIOPHARMA INC. (US) | 2015-08-04 | — | — | US | disclosed |
| CN-103450138-B | Preparation of intermidiates of 6-substituted phenoxychroman carboxylic acid derivatives | ARRAY BIOPHARMA INC | 2015-04-08 | — | — | CN | disclosed |
| EP-2826774-A1 | Intermediates for 6-substituted phenoxychroman carboxylic acid derivatives | Array Biopharma, Inc. (US) | 2015-01-21 | — | — | EP | disclosed |
| EP-2307397-B1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | ARRAY BIOPHARMA INC (US) | 2014-08-20 | — | — | EP | disclosed |
| US-20140221342-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | ARRAY BIOPHARMA INC. (US) | 2014-08-07 | — | — | US | disclosed |
| US-8716498-B2 | 6-substituted phenoxychroman carboxylic acid derivatives | ARRAY BIOPHARMA, INC. (US) | 2014-05-06 | — | — | US | disclosed |
| US-20140005418-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | ARRAY BIOPHARMA INC. (US) | 2014-01-02 | — | — | US | disclosed |
| US-8569522-B2 | 6-substituted phenoxychroman carboxylic acid derivatives | ARRAY BIOPHARMA INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-20110112288-A1 | Metal Porphyrin Catalyzed Olefin Aziridination with Sulfonyl Azides | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-05-12 | — | — | US | disclosed |
| US-20110112288-A1 | Metal Porphyrin Catalyzed Olefin Aziridination with Sulfonyl Azides | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-05-12 | — | — | US | disclosed |
| US-20110112288-A1 | Metal Porphyrin Catalyzed Olefin Aziridination with Sulfonyl Azides | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-05-12 | — | — | US | disclosed |
| US-20110105463-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | ARRAY BIOPHARMA INC. (US) | 2011-05-05 | — | — | US | disclosed |
| EP-2307397-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | Array Biopharma, Inc. (US) | 2011-04-13 | — | — | EP | disclosed |
| WO-2009158426-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | ARRAY BIOPHARMA INC. (US) | 2009-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221342-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | HRH1, HRH2, HRH4 | ALDH1A1 215/4885KMT2A 779/4885RAB9A 128/4885 |
| US-20110105463-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | GPR52, CD22, CD4 | ALDH1A1 756/4885KMT2A 466/4885RAB9A 755/4885 |
| US-20150232442-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | GPR52, CD22, CD74 | ALDH1A1 783/4885KMT2A 602/4885RAB9A 720/4885 |
| US-20140005418-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | UGT1A6, UGT2B7, UGT1A7 | ALDH1A1 67/4885KMT2A 3055/4885RAB9A 894/4885 |
| US-20110112288-A1 | Metal Porphyrin Catalyzed Olefin Aziridination with Sulfonyl Azides | PPOX, SOD1, AP1S1 | ALDH1A1 1473/4885KMT2A 3295/4885RAB9A 1892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.