Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852963 | 0.81 | PSEN1 (0.51) | KMT2AMEN1LMNAKDM4EALDH1A1 | |
| SCHEMBL2857852 | 0.75 | LMNA (0.45) | KMT2AMEN1LMNAALDH1A1MAPK1 | |
| SCHEMBL13434071 | 0.74 | KMT2A (0.70) | KMT2AMEN1LMNASMN1; SMN2KDM4E | |
| SCHEMBL5188030 | 0.72 | KMT2A (0.51) | KMT2AMEN1LMNASMN1; SMN2KDM4E | |
| SCHEMBL2857154 | 0.69 | KMT2A (0.55) | KMT2AMEN1KDM4EALDH1A1NPC1 | |
| SCHEMBL1701279 | 0.69 | KMT2A (0.76) | KMT2AMEN1LMNASMN1; SMN2KDM4E | |
| SCHEMBL13434088 | 0.69 | POLB (0.75) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7972682 | 0.68 | KMT2A (0.69) | KMT2AMEN1LMNASMN1; SMN2KDM4E | |
| SCHEMBL25852154 | 0.67 | KMT2A (0.59) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7772334 | 0.66 | KMT2A (0.71) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |