Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.50 |
| ▸ | SPR | P35270 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852963 | 0.83 | PSEN1 (0.51) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL2854321 | 0.75 | MAPT (0.53) | KMT2AHSP90AA1ALDH1A1MEN1SPR | |
| SCHEMBL2850014 | 0.73 | ALDH1A1 (0.50) | KMT2AHSP90AA1ALDH1A1MEN1SPR | |
| SCHEMBL3455287 | 0.72 | HSP90AA1 (0.66) | KMT2AHSP90AA1HPGDALDH1A1MEN1 | |
| SCHEMBL7856179 | 0.72 | KMT2A (0.73) | KMT2AHSP90AA1HPGDALDH1A1MEN1 | |
| SCHEMBL2852033 | 0.72 | LMNA (0.52) | KMT2AHPGDALDH1A1MEN1KDM4E | |
| SCHEMBL18740189 | 0.72 | KMT2A (0.48) | KMT2AHSP90AA1HPGDALDH1A1MEN1 | |
| SCHEMBL2852998 | 0.71 | NPC1 (0.59) | KMT2AHPGDALDH1A1KDM4EMAPT | |
| SCHEMBL2859853 | 0.71 | KMT2A (0.40) | KMT2AHPGDALDH1A1MEN1HTT | |
| SCHEMBL10330504 | 0.71 | KMT2A (1.00) | KMT2AHSP90AA1HPGDALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |