Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857615 | 0.87 | MTOR (0.37) | SMN1; SMN2MAPTNPC1RAB9ATDP1 | |
| SCHEMBL2852454 | 0.84 | KDM4E (0.48) | SMN1; SMN2MAPTTDP1ALDH1A1FAAH | |
| SCHEMBL2853347 | 0.84 | TRPV1 (0.41) | MAPTALDH1A1FAAHHPGDMAPK14 | |
| SCHEMBL2859091 | 0.83 | CCR1 (0.46) | NPC1RAB9AVNN1 | |
| SCHEMBL2853334 | 0.82 | CCR1 (0.47) | MAPTALDH1A1HPGDCNR1CNR2 | |
| SCHEMBL2860715 | 0.82 | ALDH1A1 (0.46) | SMN1; SMN2MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL2859298 | 0.82 | DDR1 (0.49) | SMN1; SMN2MAPTNPC1RAB9ATDP1 | |
| SCHEMBL2858156 | 0.81 | MAPT (0.41) | SMN1; SMN2MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL2857994 | 0.80 | MTOR (0.46) | MAPTNPC1RAB9ATDP1ALDH1A1 | |
| SCHEMBL2857758 | 0.80 | TRPV1 (0.41) | SMN1; SMN2MAPTNPC1RAB9ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |