Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 6/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854322 | 0.92 | ABCB1 (0.45) | CCR1MAPTP2RX7MAPK1ALDH1A1 | |
| SCHEMBL2850425 | 0.92 | P2RX7 (0.49) | CCR1MAPTP2RX7MAPK1NPSR1 | |
| SCHEMBL2853270 | 0.91 | CCR1 (0.51) | CCR1MAPTP2RX7HSP90AA1NPSR1 | |
| SCHEMBL2853388 | 0.91 | CCR1 (0.48) | CCR1CNR2MAPTP2RX7ALDH1A1 | |
| SCHEMBL2856356 | 0.91 | ALDH1A1 (0.47) | CCR1MAPTALDH1A1HPGDNPSR1 | |
| SCHEMBL2859091 | 0.91 | CCR1 (0.46) | CCR1P2RX7MAPK1 | |
| SCHEMBL2852454 | 0.90 | KDM4E (0.48) | CCR1MAPTPTGER4ALDH1A1HPGD | |
| SCHEMBL2860715 | 0.90 | ALDH1A1 (0.46) | CCR1MAPTALDH1A1HPGD | |
| SCHEMBL2858209 | 0.89 | CCR1 (0.48) | CCR1CNR1CNR2P2RX7MAPK1 | |
| SCHEMBL2848661 | 0.89 | ABCB1 (0.48) | CCR1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |