Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 8/20 | 0.41 |
| ▸ | RAB9A | P51151 | 8/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL212673 | 0.81 | MAPT (0.61) | MAPTHSD17B10ALDH1A1KMT2AFGFR1 | |
| SCHEMBL5280344 | 0.78 | HCAR3 (0.48) | MAPTHSD17B10ALDH1A1KMT2AFGFR1 | |
| SCHEMBL2019815 | 0.73 | ALDH1A1 (0.43) | MAPTHSD17B10ALDH1A1KMT2AHDAC1 | |
| SCHEMBL2296957 | 0.69 | HCAR3 (0.50) | MAPTHSD17B10ALDH1A1KMT2AFGFR1 | |
| SCHEMBL599310 | 0.69 | HCAR3 (0.65) | MAPTHSD17B10ALDH1A1KMT2AFGFR1 | |
| SCHEMBL17316372 | 0.69 | ALDH1A1 (0.55) | MAPTHSD17B10ALDH1A1KMT2AHDAC1 | |
| SCHEMBL13567899 | 0.69 | NPC1 (0.48) | MAPTHSD17B10ALDH1A1KMT2AHDAC1 | |
| SCHEMBL19911407 | 0.69 | MAPT (0.50) | MAPTHSD17B10ALDH1A1KMT2AFGFR1 | |
| SCHEMBL15088635 | 0.69 | ALDH1A1 (0.52) | MAPTHSD17B10ALDH1A1KMT2AFGFR1 | |
| SCHEMBL19553580 | 0.69 | NPC1 (0.54) | MAPTHSD17B10ALDH1A1KMT2AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112624980-B | Preparation method of bendamustine hydrochloride suitable for industrial production | 深圳万乐药业有限公司 | 2022-10-04 | — | — | CN | claimed |
| CN-112624980-A | Preparation method of bendamustine hydrochloride suitable for industrial production | 深圳万乐药业有限公司 | 2021-04-09 | — | — | CN | claimed |
| CN-112624980-B | Preparation method of bendamustine hydrochloride suitable for industrial production | 深圳万乐药业有限公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-112624980-A | Preparation method of bendamustine hydrochloride suitable for industrial production | 深圳万乐药业有限公司 | 2021-04-09 | — | — | CN | disclosed |