Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858128 | 0.91 | ALDH1A1 (0.46) | MAPK14MAPTNPC1RAB9ALMNA | |
| SCHEMBL2856893 | 0.89 | MAPT (0.43) | MAPK14MAPTNPC1RAB9ALMNA | |
| SCHEMBL2856558 | 0.88 | LMNA (0.48) | MAPK14MAPTLMNAPKMALDH1A1 | |
| SCHEMBL2858267 | 0.85 | MAPT (0.41) | MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL2856900 | 0.85 | MAPT (0.47) | MAPK14MAPTNPC1RAB9ALMNA | |
| SCHEMBL2855797 | 0.84 | CNR1 (0.47) | MAPK14MAPTLMNAPKMGAA | |
| SCHEMBL2860231 | 0.83 | CNR1 (0.50) | MAPTRAB9ALMNAPKMALDH1A1 | |
| SCHEMBL2856348 | 0.83 | MAPT (0.46) | MAPTRAB9ALMNAPKMALDH1A1 | |
| SCHEMBL2855564 | 0.83 | CNR1 (0.48) | MAPK14MAPTNPC1RAB9ALMNA | |
| SCHEMBL2860461 | 0.82 | TAAR1 (0.54) | MAPTNPC1RAB9ALMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |