SCHEMBL28548362

SCHEMBL28548362

NC(=O)c1ccc(N)cc1-c1ccc(Oc2ccc(N)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 6/20 0.54
ALDH1A1 P00352 4/20 0.45
CYP3A4 P08684 1/20 0.45
TSHR P16473 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
CHEK2 O96017 1/20 0.44
BRD4 O60885 1/20 0.43
PARP15 Q460N3 3/20 0.43
KMT2A Q03164 2/20 0.43
PARP14 Q460N5 2/20 0.43
PARP16 Q8N5Y8 1/20 0.43
PARP11 Q9NR21 1/20 0.43
PARP4 Q9UKK3 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
MAPT P10636 2/20 0.42
MEN1 O00255 1/20 0.42
MITF O75030 1/20 0.42
GAA P10253 1/20 0.42
GFER P55789 1/20 0.42
NLRP1 Q9C000 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3791222 0.90 BCAT2 (0.47) ALDH1A1CYP3A4TDP1KMT2AMAPT
SCHEMBL28905797 0.89 PARP10 (0.47) PARP10ALDH1A1CYP3A4TSHRTDP1
SCHEMBL29203839 0.88 BCAT2 (0.48) ALDH1A1CYP3A4TDP1KMT2AMAPT
SCHEMBL31506393 0.86 BCAT2 (0.47) ALDH1A1CYP3A4TDP1KMT2AMAPT
SCHEMBL7793962 0.81 PARP10 (0.52) PARP10ALDH1A1CHEK2PARP15KMT2A
SCHEMBL16741757 0.80 IKBKB (0.51) CYP3A4TDP1CHEK2KMT2AMEN1
SCHEMBL3784596 0.80 BCAT2 (0.63) ALDH1A1CYP3A4BRD4MAPTGAA
SCHEMBL29178210 0.79 PARP10 (0.49) PARP10ALDH1A1CYP3A4TSHRTDP1
SCHEMBL15170596 0.78 ALDH1A1 (0.48) ALDH1A1CYP3A4TSHRTDP1BRD4
SCHEMBL14972617 0.78 PARP10 (0.46) PARP10CHEK2BCAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112694630-B Discontinuous fiber reinforced poly-hexahydrotriazine resin-based heat-conducting composite material and preparation method thereof 华南理工大学 2022-08-12 CN disclosed
CN-112646102-B Polyhexahydrotriazine thermosetting resin containing aromatic amide structure and preparation method thereof 华南理工大学 2021-12-17 CN disclosed
CN-112694630-A Discontinuous fiber reinforced poly-hexahydrotriazine resin-based heat-conducting composite material and preparation method thereof 华南理工大学 2021-04-23 CN disclosed
CN-112646102-A Polyhexahydrotriazine thermosetting resin containing aromatic amide structure and preparation method thereof 华南理工大学 2021-04-13 CN disclosed