Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 2/20 | 0.63 |
| ▸ | IKBKB | O14920 | 4/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.51 |
| ▸ | CHUK | O15111 | 2/20 | 0.49 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.49 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.48 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29203839 | 0.90 | BCAT2 (0.48) | BCAT2IKBKBPTGDR2CHUKIKBKE | |
| SCHEMBL29771744 | 0.89 | BCAT2 (0.48) | BCAT2IKBKBPTGDR2PLA2G2APLA2G10 | |
| SCHEMBL3791222 | 0.89 | BCAT2 (0.47) | BCAT2IKBKBPTGDR2CHUKIKBKE | |
| SCHEMBL31506393 | 0.89 | BCAT2 (0.47) | BCAT2IKBKBPTGDR2CHUKIKBKE | |
| SCHEMBL3790353 | 0.87 | MAP4K4 (0.48) | BCAT2IKBKBPLA2G2APLA2G10SLCO1B1 | |
| SCHEMBL31377031 | 0.87 | MAPT (0.55) | BCAT2PTGDR2MAPTALDH1A1CYP3A4 | |
| SCHEMBL451330 | 0.87 | MAPT (0.55) | BCAT2PTGDR2MAPTALDH1A1CYP3A4 | |
| SCHEMBL7524261 | 0.87 | RORC (0.55) | BCAT2IKBKBPTGDR2NPC1RAB9A | |
| SCHEMBL3794623 | 0.85 | BCAT2 (0.63) | BCAT2IKBKBPTGDR2CHUKIKBKE | |
| Hydrochloric Acid SCHEMBL6775126 | 0.85 | MAPT (0.53) | BCAT2PTGDR2MAPTALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074378-A1 | FUNCTIONALISED AND SUBSTITUTED INDOLES AS ANTI-CANCER AGENTS | Novogen Ltd. (AU) | 2016-10-05 | — | — | EP | disclosed |
| WO-2015074123-A1 | FUNCTIONALISED AND SUBSTITUTED INDOLES AS ANTI-CANCER AGENTS | Novogen ltd (AU) | 2015-05-28 | — | — | WO | disclosed |
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | BCAT2 372/4885IKBKB 2611/4885PTGDR2 3672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.