Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL6580031 | 0.94 | CA4 (0.42) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL28981688 | 0.94 | CA4 (0.42) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL30040620 | 0.94 | CA4 (0.42) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL29577271 | 0.94 | — | — | |
| Bicarbonate SCHEMBL7906786 | 0.94 | CA4 (0.50) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL122180 | 0.94 | — | — | |
| Bicarbonate SCHEMBL43478 | 0.94 | — | — | |
| Bicarbonate SCHEMBL138735 | 0.94 | CA4 (0.50) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL29153050 | 0.89 | CA4 (0.39) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL2504262 | 0.88 | CA4 (0.46) | CA4CA1FAHD1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118754213-A | Preparation method of sulfur-phosphorus co-doped ferronickel-based hydrotalcite chloride ion battery positive electrode material | 中国矿业大学 | 2024-10-11 | — | — | CN | disclosed |
| CN-116639734-A | MnNiFe oxide nano-sheet and preparation method and application thereof | 蜂巢能源科技股份有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-111875492-B | Preparation method of organic acid anion intercalated hydrotalcite | 北京化工大学 | 2023-03-21 | — | — | CN | disclosed |
| CN-110841645-B | Synthesis method of hierarchical nanostructure iron-doped nickel oxide anode electrolysis water oxygen evolution catalyst | 南京清飏科技有限公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-110479286-B | Preparation method of titanium-iron-nickel high hydrogen evolution active electrocatalyst | 井冈山大学 | 2022-03-08 | — | — | CN | disclosed |
| CN-110479286-B | Preparation method of titanium-iron-nickel high hydrogen evolution active electrocatalyst | 井冈山大学 | 2022-03-08 | — | — | CN | disclosed |
| CN-112501647-B | Oxygen evolution reaction catalyst, preparation and application thereof, electrolysis device and seawater cracking method | 济南大学 | 2022-02-15 | — | — | CN | disclosed |
| CN-112501647-A | Oxygen evolution reaction catalyst, preparation and application thereof, electrolysis device and seawater cracking method | 济南大学 | 2021-03-16 | — | — | CN | disclosed |