Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28548383 | 0.94 | CA4 (0.46) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL10389404 | 0.94 | CA4 (0.46) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL27590118 | 0.94 | CA4 (0.46) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL17225127 | 0.89 | CA1 (0.56) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL9065873 | 0.89 | CA1 (0.56) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL6135726 | 0.89 | CA4 (0.42) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL2127368 | 0.89 | — | — | |
| Bicarbonate SCHEMBL15799393 | 0.89 | CA1 (0.56) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL9250794 | 0.89 | CA1 (0.56) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL10697570 | 0.89 | CA1 (0.56) | CA4CA1FAHD1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412284-A2 | COMPOSITION FOR TREATING CELLS AND METHODS FOR QUALITATIVELY AND QUANTITATIVELY CUSTOMIZING THE FORMULATION THEREOF FOR A HEURISTICALLY DERIVED LIVING CELL NUTRIENT-COMPOSITION-ON-DEMAND | Runkis, Walter H. (US) | 2004-04-28 | — | — | EP | claimed |
| US-20030073580-A1 | Composition for treating cells and method for qualitatively and quantitatively customizing the formulation thereof | RUNKIS WALTER H (US) | 2003-04-17 | — | — | US | claimed |
| WO-2002100772-A2 | COMPOSITION AND METHOD FOR TREATING CELLS AND PLANTS | RUNKIS WALTER H (US) | 2002-12-19 | — | — | WO | claimed |
| US-11299986-B2 | Method for acid fracturing and acid stimulation based on NMR diffusion measurements | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2022-04-12 | — | — | US | disclosed |
| US-20210238998-A1 | METHOD FOR ACID FRACTURING AND ACID STIMULATION BASED ON NMR DIFFUSION MEASUREMENTS | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2021-08-05 | — | — | US | disclosed |
| EP-2546208-B1 | Compositions providing frost appearance for printing on glass or ceramic substrates and methods for the use thereof | DIP TECH LTD (IL) | 2019-09-04 | — | — | EP | disclosed |
| US-9340448-B2 | Compositions providing frost appearance for printing on glass or ceramic substrates and methods for the use thereof | DIP TECH LTD. (IL) | 2016-05-17 | — | — | US | disclosed |
| US-20130017388-A1 | COMPOSITIONS PROVIDING FROST APPEARANCE FOR PRINTING ON GLASS OR CERAMIC SUBSTRATES AND METHODS FOR THE USE THEREOF | DIP TECH LTD. (IL) | 2013-01-17 | — | — | US | disclosed |
| EP-2546208-A1 | Compositions providing frost appearance for printing on glass or ceramic substrates and methods for the use thereof | Dip Tech. Ltd. (IL) | 2013-01-16 | — | — | EP | disclosed |
| EP-1412284-A2 | COMPOSITION FOR TREATING CELLS AND METHODS FOR QUALITATIVELY AND QUANTITATIVELY CUSTOMIZING THE FORMULATION THEREOF FOR A HEURISTICALLY DERIVED LIVING CELL NUTRIENT-COMPOSITION-ON-DEMAND | Runkis, Walter H. (US) | 2004-04-28 | — | — | EP | disclosed |
| US-20030073580-A1 | Composition for treating cells and method for qualitatively and quantitatively customizing the formulation thereof | RUNKIS WALTER H (US) | 2003-04-17 | — | — | US | disclosed |
| WO-2002100772-A2 | COMPOSITION AND METHOD FOR TREATING CELLS AND PLANTS | RUNKIS WALTER H (US) | 2002-12-19 | — | — | WO | disclosed |