Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | CASP3 | P42574 | 2/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL435522 | 0.85 | AXL (0.72) | AXLNPC1RAB9AKDM4EMAPT | |
| SCHEMBL13541757 | 0.80 | TNKS2 (0.49) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL27765641 | 0.79 | FGFR1 (0.50) | HSD17B1HSD17B2ESR2 | |
| SCHEMBL20615410 | 0.79 | TNKS2 (0.50) | AXL | |
| SCHEMBL18000095 | 0.77 | PDE3B (0.50) | NPC1RAB9A | |
| SCHEMBL28147639 | 0.77 | HSD17B1 (0.68) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL30071213 | 0.76 | FLT3 (0.55) | NPC1RAB9AKDM4EMAPTHPGD | |
| SCHEMBL20494459 | 0.76 | FLT3 (0.55) | NPC1RAB9AKDM4EMAPTHPGD | |
| SCHEMBL20495078 | 0.75 | NPC1 (0.55) | NPC1RAB9AKDM4EMAPTALDH1A1 | |
| SCHEMBL30071254 | 0.75 | NPC1 (0.55) | NPC1RAB9AKDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112047871-B | Preparation method of indole compound | 南京大学 | 2022-06-21 | — | — | CN | disclosed |
| CN-112047871-A | Preparation method of indole compound | 南京大学 | 2020-12-08 | — | — | CN | disclosed |