Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21166584 | 0.89 | TLR8 (0.42) | TLR8MAPTALOX15MEN1KMT2A | |
| SCHEMBL12277853 | 0.84 | MAPT (0.46) | TLR8MAPTALOX15MEN1KMT2A | |
| SCHEMBL12278503 | 0.81 | MAPT (0.46) | TLR8MAPTALOX15MEN1KMT2A | |
| SCHEMBL12370192 | 0.80 | TLR8 (0.44) | TLR8MAPTALOX15F2F10 | |
| SCHEMBL12278377 | 0.79 | MAPT (0.51) | TLR8MAPTALOX15CA12CA1 | |
| SCHEMBL29594271 | 0.79 | LOXL2 (0.56) | TLR8MAPTSMN1; SMN2 | |
| SCHEMBL1287509 | 0.79 | LOXL2 (0.56) | TLR8MAPTSMN1; SMN2 | |
| SCHEMBL284155 | 0.78 | TLR8 (0.50) | TLR8MAPTALOX15MEN1KMT2A | |
| SCHEMBL2333763 | 0.78 | CYP19A1 (0.47) | TLR8MAPTALOX15F2F10 | |
| SCHEMBL6741629 | 0.78 | ALOX15 (0.55) | TLR8MAPTALOX15MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112679515-A | Benzofuran derivative and preparation method and application thereof | 苏聪 | 2021-04-20 | — | — | CN | claimed |
| CN-112679515-A | Benzofuran derivative and preparation method and application thereof | 苏聪 | 2021-04-20 | — | — | CN | disclosed |