Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.39 |
| ▸ | LIPE | Q05469 | 5/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853624 | 0.86 | NOTUM (0.49) | HSD11B1EPHX1MGLLFFAR4 | |
| SCHEMBL18825722 | 0.72 | FFAR4 (0.57) | KCNA5FFAR4 | |
| Hydrochloric Acid SCHEMBL16742024 | 0.69 | LGMN (0.42) | EPHX2 | |
| SCHEMBL2687452 | 0.69 | CHRNB2 (0.40) | — | |
| SCHEMBL16695431 | 0.69 | FFAR4 (0.45) | EPHX2EPHX1FFAR4 | |
| SCHEMBL12696715 | 0.68 | SCN9A (0.44) | KCNA5EPHX2FFAR4 | |
| SCHEMBL3176461 | 0.68 | POLB (0.42) | — | |
| SCHEMBL20840880 | 0.67 | EPHX2 (0.46) | EPHX2LIPEEPHX1FFAR4 | |
| SCHEMBL30022640 | 0.66 | KCNA5 (0.51) | KCNA5 | |
| SCHEMBL12717115 | 0.65 | FFAR4 (0.72) | FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |