Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28551647 | 0.85 | — | — | |
| SCHEMBL28543435 | 0.76 | PNP (0.37) | HSD11B1 | |
| SCHEMBL17814738 | 0.69 | TNF (0.42) | KDM4EMEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL18950494 | 0.59 | CDC25A (0.37) | MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL1047702 | 0.59 | CDC25A (0.37) | MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL1048937 | 0.57 | NPC1 (0.38) | MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL27173413 | 0.56 | HDAC4 (0.44) | BACE1HSD11B1 | |
| SCHEMBL10743825 | 0.55 | CYP19A1 (0.57) | HSD11B1KDM4E | |
| SCHEMBL1975025 | 0.54 | HSD11B1 (0.56) | HSD11B1KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL5253993 | 0.53 | CCR2 (0.49) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409331-B | Heterocyclic derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-112409331-A | Heterocyclic derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2021-02-26 | — | — | CN | disclosed |