Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.39 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.37 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28562235 | 0.90 | CHEK2 (0.39) | CHEK2CTPS1MAPTTP53HTT | |
| SCHEMBL25291390 | 0.87 | LMNA (0.35) | CHEK2CTPS1MAPTTP53HTT | |
| SCHEMBL28548767 | 0.85 | MAPT (0.37) | RBP4CHEK2CTPS1MAPTTP53 | |
| SCHEMBL25251188 | 0.84 | MAPT (0.34) | CTPS1MAPTTP53HTTLMNA | |
| SCHEMBL31454691 | 0.83 | LMNA (0.36) | CTPS1MAPTTP53HTTLMNA | |
| SCHEMBL19436516 | 0.83 | GPR119 (0.49) | CHEK2GPR119SCN9ANR1D1 | |
| SCHEMBL25298309 | 0.82 | NR1D1 (0.40) | CHEK2CTPS1MAPTTP53HTT | |
| SCHEMBL28562237 | 0.82 | PDK1 (0.38) | CTPS1MAPTTP53HTTLMNA | |
| SCHEMBL25301553 | 0.81 | CHEK2 (0.41) | CHEK2MAPTSCN9ANR1D1ALDH1A1 | |
| SCHEMBL30803074 | 0.81 | PARP15 (0.46) | CTPS1MAPTTP53HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110016021-B | Immunomodulator | 成都先导药物开发股份有限公司 | 2021-05-07 | — | — | CN | disclosed |