Benzo[1,2,5]Thiadiazole

Benzo[1,2,5]Thiadiazole

SCHEMBL28548839

C=CCc1csc(-c2cccs2)c1.c1ccc2nsnc2c1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 11/20 0.40
ALDH1A1 P00352 10/20 0.40
HSD17B10 Q99714 6/20 0.40
HPGD P15428 6/20 0.40
MAPT P10636 4/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
TSHR P16473 2/20 0.40
SMN1; SMN2 Q16637 5/20 0.38
GAA P10253 2/20 0.38
CASP1 P29466 2/20 0.38
CASP7 P55210 2/20 0.38
GLA P06280 2/20 0.38
TP53 P04637 2/20 0.38
RPS6KB2 Q9UBS0 1/20 0.35
PTPN1 P18031 1/20 0.35
PTPN11 Q06124 1/20 0.35
NPC1 O15118 6/20 0.34
RAB9A P51151 6/20 0.34
ATM Q13315 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzo[1,2,5]Thiadiazole SCHEMBL28556445 0.81 RXFP1 (0.36) KDM4EALDH1A1HSD17B10HPGDMAPT
Benzo[1,2,5]Thiadiazole SCHEMBL29002170 0.77 HPGD (0.37) KDM4EALDH1A1HSD17B10HPGDMAPT
SCHEMBL1327338 0.75 XDH (0.39) KDM4EALDH1A1HPGDMAPTMEN1
SCHEMBL17967427 0.68 LTA4H (0.40) KDM4EALDH1A1HSD17B10HPGDMAPT
Allylbenzene SCHEMBL28604670 0.67 NPC1 (0.38) KDM4EALDH1A1HSD17B10HPGDMAPT
SCHEMBL10564184 0.66 LTA4H (0.61) KDM4EALDH1A1HSD17B10HPGDMAPT
SCHEMBL7874427 0.65 SREBF2 (0.42) KDM4EALDH1A1MAPTKMT2AGAA
SCHEMBL14660080 0.65 MAPT (0.33) KDM4EALDH1A1HPGDMAPTMEN1
SCHEMBL26066562 0.64 PRMT6 (0.37) KDM4EALDH1A1HSD17B10HPGDMAPT
Allylbenzene SCHEMBL27945193 0.64 KDM4E (0.36) KDM4EALDH1A1HSD17B10HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112500556-B Donor-receptor type electrochromic polymer, preparation method, electrochromic film and application 上海戎科特种装备有限公司 2023-03-21 CN claimed
CN-112500556-A Donor-receptor type electrochromic polymer, preparation method, electrochromic film and application 上海戎科特种装备有限公司 2021-03-16 CN claimed
CN-112500556-B Donor-receptor type electrochromic polymer, preparation method, electrochromic film and application 上海戎科特种装备有限公司 2023-03-21 CN disclosed
CN-112500556-A Donor-receptor type electrochromic polymer, preparation method, electrochromic film and application 上海戎科特种装备有限公司 2021-03-16 CN disclosed