Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9951657 | 0.87 | ALDH1A1 (0.50) | ALDH1A1HTTHPGDSMN1; SMN2LMNA | |
| SCHEMBL28548830 | 0.83 | RAB9A (0.45) | ALDH1A1HTTHPGDNPC1RAB9A | |
| SCHEMBL20554083 | 0.82 | ALDH1A1 (0.51) | ALDH1A1HTTCA12CA1CA2 | |
| SCHEMBL20554293 | 0.82 | ALDH1A1 (0.46) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL1458301 | 0.76 | HSD17B2 (0.61) | HSD17B2ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18031363 | 0.75 | HSD17B2 (0.51) | HSD17B2ALDH1A1HTTNPC1RAB9A | |
| SCHEMBL1094691 | 0.75 | NPC1 (0.65) | ALDH1A1HTTHPGDNPC1RAB9A | |
| SCHEMBL23904824 | 0.74 | HSD17B2 (0.47) | HSD17B2HTTNPC1RAB9AKMT2A | |
| SCHEMBL20094718 | 0.74 | RAB9A (0.48) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9952440 | 0.74 | KDM4E (0.42) | ALDH1A1HTTHPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108341822-B | FXR receptor modulator and preparation method and application thereof | 广州市恒诺康医药科技有限公司 | 2021-04-16 | — | — | CN | disclosed |