Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20951881 | 0.85 | SMN1; SMN2 (0.48) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL20554184 | 0.85 | SMN1; SMN2 (0.51) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL22654681 | 0.84 | SMN1; SMN2 (0.45) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL19899989 | 0.84 | ALDH1A1 (0.47) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL28548876 | 0.83 | HSD17B2 (0.47) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL20554157 | 0.79 | NR1H4 (0.39) | GAALMNA | |
| SCHEMBL20952011 | 0.76 | SMN1; SMN2 (0.44) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL1094691 | 0.76 | NPC1 (0.65) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL20943936 | 0.76 | CA12 (0.44) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL30617282 | 0.74 | RAB9A (0.37) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108341822-B | FXR receptor modulator and preparation method and application thereof | 广州市恒诺康医药科技有限公司 | 2021-04-16 | — | — | CN | disclosed |