Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29622190 | 0.80 | KMT2A (0.56) | ALDH1A1SMN1; SMN2GAAHTTRAB9A | |
| SCHEMBL29622620 | 0.76 | MEN1 (0.48) | ALDH1A1SMN1; SMN2GAAHTTRAB9A | |
| SCHEMBL15077769 | 0.75 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2GAAHTTRAB9A | |
| SCHEMBL8837656 | 0.74 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2GAAHTTRAB9A | |
| SCHEMBL11796988 | 0.73 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2GAAHTTRAB9A | |
| SCHEMBL19063563 | 0.73 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2GAAHTTRAB9A | |
| SCHEMBL8620552 | 0.72 | SMN1; SMN2 (0.56) | ALDH1A1SMN1; SMN2GAAHTTRAB9A | |
| SCHEMBL22204354 | 0.69 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2GAAHTTRAB9A | |
| SCHEMBL31527768 | 0.69 | ATM (0.77) | ALDH1A1SMN1; SMN2GAAHTTRAB9A | |
| SCHEMBL282531 | 0.69 | SMN1; SMN2 (0.71) | ALDH1A1SMN1; SMN2GAAHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022117075-A1 | AZACYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 广州费米子科技有限责任公司 | 2022-06-09 | — | — | WO | disclosed |
| CN-113698404-A | Hexahydrocyclopenta [ c ] pyrrole-2 (1H) -formamide compound with low solvent residue and preparation method thereof | 江苏恒瑞医药股份有限公司 | 2021-11-26 | — | — | CN | disclosed |
| CN-108884100-B | Preparation method and intermediate of pyrrolo six-membered heteroaromatic ring derivative | 江苏恒瑞医药股份有限公司 | 2021-04-06 | — | — | CN | disclosed |