Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11796988 | 0.86 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2GAAHTTRAB9A | |
| SCHEMBL8620552 | 0.81 | SMN1; SMN2 (0.56) | ALDH1A1SMN1; SMN2GAAHTTRAB9A | |
| SCHEMBL9542988 | 0.79 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2GAAHTTL3MBTL1 | |
| SCHEMBL2893620 | 0.77 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2GAAHTTATM | |
| SCHEMBL28548950 | 0.74 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2GAAHTTATM | |
| SCHEMBL8673149 | 0.73 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2GAAHTTATM | |
| SCHEMBL7556781 | 0.73 | HSP90AA1 (0.59) | ALDH1A1SMN1; SMN2GAAHTTRAB9A | |
| SCHEMBL31527768 | 0.71 | ATM (0.77) | ALDH1A1SMN1; SMN2GAAHTTATM | |
| SCHEMBL22204354 | 0.71 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2GAAHTTRAB9A | |
| SCHEMBL25533213 | 0.71 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2HTTMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597779-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1997-01-28 | — | — | US | disclosed |
| US-5552368-A | Sulfonylureas | CIBA-GEIGY CORPORATION (US) | 1996-09-03 | — | — | US | disclosed |
| US-5519148-A | CHEMICAL INTERMEDIATES FOR HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1996-05-21 | — | — | US | disclosed |
| US-5489695-A | PREEMERGENCE, POSTEMERGENCE HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1996-02-06 | — | — | US | disclosed |
| US-5412107-A | Phenylsulfonylchloride intermediates useful for the preparation of herbicidally active sulfonylureas | CIBA-GEIGY CORPORATION (US) | 1995-05-02 | — | — | US | disclosed |
| US-5286709-A | Sulfonylureas | CIBA-GEIGY CORPORATION (US) | 1994-02-15 | — | — | US | disclosed |
| US-5209771-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1993-05-11 | — | — | US | disclosed |