SCHEMBL8620552

SCHEMBL8620552

COc1cc(OC)nc(OC(=O)Nc2ccccc2)n1

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.56
ALDH1A1 P00352 3/20 0.56
GAA P10253 1/20 0.56
HTT P42858 1/20 0.56
KMT2A Q03164 4/20 0.47
NPC1 O15118 1/20 0.47
MEN1 O00255 1/20 0.46
EDNRB P24530 3/20 0.46
EDNRA P25101 3/20 0.46
MAPT P10636 2/20 0.46
BCHE P06276 1/20 0.46
ACHE P22303 1/20 0.46
RAB9A P51151 1/20 0.46
CYP1A2 P05177 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9542988 0.92 SMN1; SMN2 (0.51) SMN1; SMN2ALDH1A1GAAHTTKMT2A
SCHEMBL27427330 0.84 SMN1; SMN2 (0.63) SMN1; SMN2ALDH1A1GAAHTTKMT2A
SCHEMBL11796988 0.84 ALDH1A1 (0.56) SMN1; SMN2ALDH1A1GAAHTTKMT2A
SCHEMBL8837656 0.81 ALDH1A1 (0.55) SMN1; SMN2ALDH1A1GAAHTTKMT2A
SCHEMBL11342623 0.78 SMN1; SMN2 (0.59) SMN1; SMN2ALDH1A1KMT2ANPC1MEN1
SCHEMBL27600380 0.77 CYP1A2 (0.58) SMN1; SMN2ALDH1A1GAAKMT2ANPC1
SCHEMBL13201041 0.77 LMNA (0.60) SMN1; SMN2ALDH1A1GAAKMT2ANPC1
SCHEMBL8584199 0.76 KDM4E (0.51) ALDH1A1GAAKMT2AMEN1EDNRB
SCHEMBL1576702 0.76 MAPT (0.59) SMN1; SMN2ALDH1A1GAAHTTKMT2A
SCHEMBL12095279 0.75 EDNRB (0.49) SMN1; SMN2ALDH1A1KMT2AEDNRBEDNRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5736628-A HERBICIDE KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1998-04-07 US disclosed
EP-0444101-B1 PROCESS FOR THE INTERCONVERSION OF TWO SEPARATE CRYSTAL FORMS OF A HERBICIDAL PYRIDINE SULFONAMIDE DU PONT (US) 1996-09-18 EP disclosed
US-5461025-A Herbicides KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1995-10-24 US disclosed
US-5296453-A Dry flowable preparation formed by hydrating herbicide in presence of heat E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-03-22 US disclosed
EP-0314505-B1 Herbicidal pyridine sulfonylureas DU PONT (US) 1994-02-16 EP disclosed
EP-0237292-B1 Herbicidal pyridine sulfonamides DU PONT (US) 1994-02-02 EP disclosed
EP-0575378-A1 BENZENESULFONYLUREA DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1993-12-29 EP disclosed
EP-0547035-A1 Pyridinecarboxamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-06-16 EP disclosed
US-5202439-A Hydrating in presence of heat E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-04-13 US disclosed
US-5160363-A For sugarbeets E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-11-03 US disclosed
WO-1990005728-A1 PROCESS FOR THE INTERCONVERSION OF TWO SEPARATE CRYSTAL FORMS OF A HERBICIDAL PYRIDINE SULFONAMIDE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-05-31 WO disclosed
EP-0346334-A1 HERBICIDAL PYRIDINE SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-12-20 EP disclosed
WO-1989010921-A1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-11-16 WO disclosed
US-4838926-A Herbicidal pyridine sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-06-13 US disclosed
US-4789393-A SAFE TO CORN E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-12-06 US disclosed
US-4786734-A FOR GRASSES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-11-22 US disclosed
WO-1988004655-A2 HERBICIDAL PYRIDINE SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-06-30 WO disclosed
US-4741765-A Herbicidal sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-05-03 US disclosed
CN-87103399-A The preparation of sulfonylurea herbicide, composition, content and application 1987-12-16 CN disclosed
US-4678499-A PRE- AND POSTEMERGENCE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-07-07 US disclosed