Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | G6PD | P11413 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.30 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20973018 | 0.74 | NOTUM (0.46) | NOTUMNPC1GAAKDM4EADORA2A | |
| SCHEMBL28553753 | 0.74 | CYP1A2 (0.38) | NOTUMNPC1RAB9AKDM4EMAPT | |
| SCHEMBL159734 | 0.70 | NOTUM (0.41) | NOTUMNPC1RAB9AGAAKDM4E | |
| SCHEMBL1586320 | 0.68 | NOTUM (0.38) | NOTUMNPC1RAB9AGAAKDM4E | |
| SCHEMBL2884958 | 0.66 | ALDH1A1 (0.39) | KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL159595 | 0.66 | ALDH1A1 (0.39) | GAAKDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL1586140 | 0.65 | NOTUM (0.38) | NOTUMNPC1GAAKDM4EMAPT | |
| SCHEMBL1404600 | 0.65 | NOTUM (0.55) | NOTUMNPC1GAAKDM4EADORA2A | |
| SCHEMBL8682848 | 0.64 | ALDH1A1 (0.38) | KDM4EALDH1A1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL831500 | 0.64 | ALDH1A1 (0.38) | KDM4EALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531685-B | Compounds with antitumor activity | AB科学有限公司 | 2021-04-23 | — | — | CN | disclosed |