Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL159595 | 0.82 | ALDH1A1 (0.39) | ALDH1A1KDM4EHSD17B10HTR1AHTR1D | |
| SCHEMBL8682848 | 0.80 | ALDH1A1 (0.38) | ALDH1A1KDM4EHSD17B10TSHRMAPK1 | |
| SCHEMBL831500 | 0.80 | ALDH1A1 (0.38) | ALDH1A1KDM4EHSD17B10TSHRMAPK1 | |
| SCHEMBL719277 | 0.78 | ALDH1A1 (0.37) | ALDH1A1KDM4EHSD17B10TSHRMAPK1 | |
| SCHEMBL2355429 | 0.70 | ALDH1A1 (0.50) | ALDH1A1KDM4EHSD17B10HTR1AHTR1D | |
| SCHEMBL29536407 | 0.70 | ALDH1A1 (0.50) | ALDH1A1KDM4EHSD17B10HTR1AHTR1D | |
| SCHEMBL2884395 | 0.69 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL11484541 | 0.69 | ALDH1A1 (0.48) | ALDH1A1KDM4EHSD17B10HTR1AHTR1D | |
| SCHEMBL221144 | 0.68 | — | — | |
| SCHEMBL8531806 | 0.67 | CYP1B1 (0.40) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7057061-B2 | Chiral monophosphorus compounds | BAYER AKTIENGESELLSCHAFT (DE) | 2006-06-06 | — | — | US | claimed |
| US-20030119664-A1 | Chiral monophosphorus compounds | LANXESS DEUTSCHLAND GMBH (DE) | 2003-06-26 | — | — | US | claimed |
| US-7847126-B2 | prepared by reacting phosphorus halide with organomagnesium compound in presence of copper compound; di(tert-butyl)phenylphosphonium tetrafluoroborate, for example | LANXESS DEUTSCHLAND GMBH (DE) | 2010-12-07 | — | — | US | disclosed |
| US-20070299273-A1 | prepared by reacting phosphorus halide with organomagnesium compound in presence of copper compound; di(tert-butyl)phenylphosphonium tetrafluoroborate, for example | LANXESS DEUTSCHLAND GMBH (DE) | 2007-12-27 | — | — | US | disclosed |
| US-7230136-B2 | Reacting phosphorus halide with organomagnesium compound in presence of copper compound | LANXESS DEUTSCHLAND GMBH (DE) | 2007-06-12 | — | — | US | disclosed |
| US-7057061-B2 | Chiral monophosphorus compounds | BAYER AKTIENGESELLSCHAFT (DE) | 2006-06-06 | — | — | US | disclosed |
| US-20030229240-A1 | Reacting phosphorus halide with organomagnesium compound in presence of copper compound | LANXESS DEUTSCHLAND GMBH (DE) | 2003-12-11 | — | — | US | disclosed |
| EP-1354886-A1 | Process for the preparation of tertiary phosphines | Bayer Aktiengesellschaft (DE) | 2003-10-22 | — | — | EP | disclosed |
| US-20030119664-A1 | Chiral monophosphorus compounds | LANXESS DEUTSCHLAND GMBH (DE) | 2003-06-26 | — | — | US | disclosed |