SCHEMBL831500

SCHEMBL831500

COc1[c]ccc(Cl)c1OC

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
KDM4E B2RXH2 2/20 0.38
HSD17B10 Q99714 1/20 0.38
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
DRD2 P14416 1/20 0.30
DRD1 P21728 1/20 0.30
DRD5 P21918 1/20 0.30
DRD3 P35462 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL159595 0.80 ALDH1A1 (0.39) ALDH1A1KDM4EHSD17B10TSHRMAPK1
SCHEMBL2884958 0.80 ALDH1A1 (0.39) ALDH1A1KDM4EHSD17B10TSHRMAPK1
SCHEMBL221144 0.80
SCHEMBL8682848 0.78 ALDH1A1 (0.38) ALDH1A1KDM4EHSD17B10TSHRMAPK1
SCHEMBL8120627 0.78 ALDH1A1 (0.31) ALDH1A1
SCHEMBL719277 0.77 ALDH1A1 (0.37) ALDH1A1KDM4EHSD17B10TSHRMAPK1
SCHEMBL2344169 0.77 HTR2A (0.31)
SCHEMBL77640 0.76 CA9 (0.35) ALDH1A1KDM4EMAPK1SMN1; SMN2
SCHEMBL8196392 0.76 KDM4E (0.32) ALDH1A1KDM4EMAPK1SMN1; SMN2
SCHEMBL22575947 0.74 CA2 (0.35) ALDH1A1KDM4ETSHRMAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0816439-B1 Water-insoluble azo colouring agents derived from N-acetoacetyldehydrothiotoluidine CLARIANT GMBH (DE) 2000-10-04 EP claimed
US-5756691-A YELLOW HOECHST AKTIENGESELLSCHAFT (DE) 1998-05-26 US claimed
EP-0816439-A1 Water-insoluble azo colouring agents derived from N-acetoacetyldehydrothiotoluidine Clariant GmbH (DE) 1998-01-07 EP claimed
EP-0320201-B1 1,2,4,5-Benzoylenebis (naphto [2,3-d] imidazole) compounds and photosensitive members containing them SHARP KK (JP) 1994-02-09 EP claimed
US-4629793-A 2,3-di-substituted-5,6-dihydroimidazo [2,1-b] thiazole, its salts, production thereof and anti-inflammatory agent containing the same TOYO JOZO KABUSHIKI KAISHA (JP) 1986-12-16 US claimed
EP-0012611-B1 ELECTROPHOTOGRAPHIC ELEMENT Ricoh Company, Ltd (JP) 1983-10-05 EP claimed
US-4348470-A IN CHARGE GENERATING LAYER RICOH CO., LTD. (JP) 1982-09-07 US claimed
US-4314015-A Electrophotographic sensitive materials containing disazo compounds RICOH CO., LTD. (JP) 1982-02-02 US claimed
US-4299896-A Electrophotographic sensitive materials containing a disazo pigment RICOH CO., LTD. (JP) 1981-11-10 US claimed
US-4293628-A Electrophotographic elements containing disazo compounds RICOH CO., LTD. (JP) 1981-10-06 US claimed
US-4279981-A Electrophotographic elements containing trisazo compounds RICOH COMPANY, LTD. (JP) 1981-07-21 US claimed
US-4272598-A STYRYL DYES RICOH CO., LTD. (JP) 1981-06-09 US claimed
US-4260672-A Electrophotographic sensitive element having a photoconductive disazo pigment RICOH COMPANY, LTD. (JP) 1981-04-07 US claimed
US-4251614-A CARBAZOLE DERIVATIVES RICOH COMPANY, LTD. (JP) 1981-02-17 US claimed
US-4251613-A LAMINATE OF CONDUCTIVE SUPPORT AND PHOTOSENSITIVE LAYER RICOH COMPANY, LTD. (JP) 1981-02-17 US claimed
US-4250319-A RIPENER FOR SUGARCANE W. R. GRACE & CO. (US) 1981-02-10 US claimed
EP-0012611-A2 Electrophotographic element Ricoh Company, Ltd (JP) 1980-06-25 EP claimed
US-4010162-A Substituted phenanthroline pigments ALLIED CHEMICAL CORPORATION (US) 1977-03-01 US claimed
US-8143295-B2 Compounds having activity in correcting mutant-CFTR processing and uses thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-03-27 US disclosed
EP-0012611-A2 Electrophotographic element Ricoh Company, Ltd (JP) 1980-06-25 EP disclosed