Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28557786 | 0.98 | ALDH1A1 (0.47) | MAPTLMNAPOLBGAAALDH1A1 | |
| SCHEMBL9330752 | 0.81 | LMNA (0.51) | MAPTLMNAPOLBGAAALDH1A1 | |
| SCHEMBL31730148 | 0.76 | LMNA (0.43) | MAPTLMNAPOLBGAAALDH1A1 | |
| SCHEMBL6434415 | 0.75 | ESR2 (0.48) | ALOX12 | |
| SCHEMBL8381617 | 0.75 | DDB1 (0.50) | SLC18A3KMT2A | |
| SCHEMBL19993834 | 0.75 | LMNA (0.42) | MAPTLMNAPOLBGAAMEN1 | |
| SCHEMBL513149 | 0.75 | LMNA (0.42) | LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL1616775 | 0.75 | KDM4E (0.42) | MAPTPOLBALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL1138156 | 0.75 | NPC1 (0.45) | MAPTLMNAGAAALDH1A1TP53 | |
| SCHEMBL28649636 | 0.75 | TLR4 (0.42) | MAPTSLC18A3EPHX1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232149-B | Synthetic method of alpha-fluoro-alpha-substituted ketone with fluorine-containing quaternary carbon central structure | 兰州大学 | 2021-04-02 | — | — | CN | disclosed |