Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 4/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | FABP3 | P05413 | 2/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.45 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30462500 | 1.00 | FABP4 (0.52) | FABP4MAPK8FABP3FABP5TAS2R14 | |
| SCHEMBL30462447 | 0.85 | PBRM1 (0.54) | FABP4MAPK8FABP3FABP5SIRT2 | |
| SCHEMBL28553681 | 0.85 | PBRM1 (0.54) | FABP4MAPK8FABP3FABP5SIRT2 | |
| SCHEMBL3398683 | 0.84 | THRA (0.45) | FABP4MAPK8CXCR5KDM4EKDM5A | |
| SCHEMBL28557288 | 0.81 | MAPK8 (0.53) | FABP4MAPK8FABP3FABP5SIRT2 | |
| SCHEMBL30462481 | 0.81 | MAPK8 (0.56) | FABP4MAPK8FABP3FABP5SIRT2 | |
| SCHEMBL30462462 | 0.81 | MAPK8 (0.53) | FABP4MAPK8FABP3FABP5SIRT2 | |
| SCHEMBL28563343 | 0.81 | MAPK8 (0.56) | FABP4MAPK8FABP3FABP5SIRT2 | |
| SCHEMBL28559723 | 0.81 | MAPK8 (0.46) | FABP4MAPK8FABP3FABP5TAS2R14 | |
| SCHEMBL30462460 | 0.81 | MAPK8 (0.46) | FABP4MAPK8FABP3FABP5TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112745237-B | 2-arylamine compound and preparation method and application thereof | 中国科学院上海药物研究所 | 2023-06-20 | — | — | CN | disclosed |
| CN-112745237-A | 2-arylamine compound and preparation method and application thereof | 中国科学院上海药物研究所 | 2021-05-04 | — | — | CN | disclosed |