Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PMM2 | O15305 | 3/20 | 0.44 |
| ▸ | MPI | P34949 | 3/20 | 0.44 |
| ▸ | PHOSPHO1 | Q8TCT1 | 3/20 | 0.44 |
| ▸ | CASP3 | P42574 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | G6PD | P11413 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9263852 | 0.93 | PHOSPHO1 (0.47) | KAT2BALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL9256085 | 0.83 | PMM2 (0.45) | KAT2BALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL9256001 | 0.79 | KDM4E (0.40) | KAT2BALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL28551232 | 0.77 | KAT2B (0.46) | KAT2BALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL9262493 | 0.76 | MAPT (0.46) | ALDH1A1NPC1RAB9AKDM4EMAPT | |
| SCHEMBL9263510 | 0.73 | SMN1; SMN2 (0.60) | KAT2BALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL9258084 | 0.73 | ALDH1A1 (0.43) | KAT2BALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL1955264 | 0.72 | NPSR1 (0.43) | KAT2BALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL12632651 | 0.70 | KAT2B (0.61) | KAT2BALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL11193393 | 0.69 | KAT2B (0.60) | KAT2BALDH1A1KDM4EHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110066254-B | Preparation method of isothiazole-3-ketone compound | 温州大学 | 2021-03-19 | — | — | CN | disclosed |