Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MPO | P05164 | 1/20 | 0.30 |
| ▸ | TPO | P07202 | 1/20 | 0.30 |
| ▸ | EPX | P11678 | 1/20 | 0.30 |
| ▸ | LPO | P22079 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28551684 | 0.82 | BCL2L1 (0.41) | LMNASMN1; SMN2 | |
| SCHEMBL26077231 | 0.78 | RAB9A (0.33) | SMN1; SMN2 | |
| SCHEMBL21551338 | 0.77 | NR1H2 (0.42) | SMN1; SMN2 | |
| SCHEMBL21564351 | 0.77 | CARM1 (0.35) | — | |
| SCHEMBL30931762 | 0.77 | NR1H2 (0.42) | SMN1; SMN2 | |
| SCHEMBL21551301 | 0.72 | TACR1 (0.36) | SMN1; SMN2 | |
| SCHEMBL21551302 | 0.71 | TOP2A (0.37) | — | |
| SCHEMBL30931855 | 0.69 | HTR2C (0.35) | — | |
| SCHEMBL21564354 | 0.69 | HTR2C (0.35) | — | |
| SCHEMBL17157314 | 0.65 | LIPE (0.43) | LTA4HLMNACYP2C9TSHRAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384509-B | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-112384509-A | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-02-19 | — | — | CN | disclosed |