Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21551338 | 1.00 | NR1H2 (0.42) | NR1H2NR1H3ALDH1A1MEN1MAPT | |
| SCHEMBL26077248 | 0.79 | RAB9A (0.43) | NR1H2NR1H3ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL20616269 | 0.79 | L3MBTL1 (0.52) | NR1H2NR1H3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21551302 | 0.77 | TOP2A (0.37) | P2RX3BCL2L1MCL1 | |
| SCHEMBL28550707 | 0.77 | LTA4H (0.33) | SMN1; SMN2 | |
| SCHEMBL21551431 | 0.77 | KMT2A (0.46) | NR1H2NR1H3MEN1KMT2A | |
| SCHEMBL21564351 | 0.76 | CARM1 (0.35) | — | |
| SCHEMBL30931853 | 0.76 | FURIN (0.47) | NR1H2NR1H3 | |
| SCHEMBL21551301 | 0.76 | TACR1 (0.36) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL21551153 | 0.76 | FURIN (0.47) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384509-B | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2024-04-30 | — | — | CN | disclosed |