Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL638342 | 0.97 | TSHR (0.39) | MEN1KMT2ALMNATSHRMAPK1 | |
| Water SCHEMBL1358543 | 0.94 | TSHR (0.37) | MEN1KMT2ALMNATSHRMAPK1 | |
| Fluoride Ion SCHEMBL190628 | 0.94 | TSHR (0.37) | MEN1KMT2ALMNATSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL2444153 | 0.94 | CYP3A4 (0.38) | MEN1KMT2ALMNATSHRMAPK1 | |
| Fluoride SCHEMBL27656504 | 0.94 | TSHR (0.37) | MEN1KMT2ALMNATSHRMAPK1 | |
| Water SCHEMBL11035195 | 0.91 | TSHR (0.35) | MEN1KMT2ALMNATSHRMAPK1 | |
| SCHEMBL27656499 | 0.86 | ALDH1A1 (0.32) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL5044768 | 0.86 | ALDH1A1 (0.32) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL3750721 | 0.84 | ALDH1A1 (0.31) | TSHRMAPK1ALDH1A1GALR3 | |
| Sulfuric Acid SCHEMBL27564936 | 0.84 | ALDH1A1 (0.31) | TSHRMAPK1ALDH1A1GALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109553904-B | Use of quaternary ammonium salts with hydroxyethyl groups in polyvinyl alcohol processing | 怀化学院 | 2021-07-20 | — | — | CN | disclosed |
| CN-109485915-B | Additive for processing polyvinyl alcohol and preparation method thereof | 怀化学院 | 2021-03-02 | — | — | CN | disclosed |