Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL638342 | 0.97 | TSHR (0.39) | CYP3A4SLC5A7TSHRMAPK1ALDH1A1 | |
| Bromide SCHEMBL28550756 | 0.94 | MEN1 (0.38) | CYP3A4SLC5A7TSHRMAPK1ALDH1A1 | |
| Fluoride Ion SCHEMBL190628 | 0.94 | TSHR (0.37) | CYP3A4SLC5A7TSHRMAPK1ALDH1A1 | |
| Water SCHEMBL1358543 | 0.94 | TSHR (0.37) | CYP3A4SLC5A7TSHRMAPK1ALDH1A1 | |
| Fluoride SCHEMBL27656504 | 0.94 | TSHR (0.37) | CYP3A4SLC5A7TSHRMAPK1ALDH1A1 | |
| Water SCHEMBL11035195 | 0.91 | TSHR (0.35) | CYP3A4SLC5A7TSHRMAPK1ALDH1A1 | |
| SCHEMBL27656499 | 0.86 | ALDH1A1 (0.32) | TSHRMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL5044768 | 0.86 | ALDH1A1 (0.32) | TSHRMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL3750721 | 0.84 | ALDH1A1 (0.31) | TSHRMAPK1ALDH1A1GALR3 | |
| Sulfuric Acid SCHEMBL27564936 | 0.84 | ALDH1A1 (0.31) | TSHRMAPK1ALDH1A1GALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6379500-B2 | Silica-based sols | AKZO NOBEL NV (NL) | 2002-04-30 | — | — | US | claimed |
| US-20010004927-A1 | Aqueous silica-based sol comprising a nitrogen-containing organic compound and silica-based particles with a specific surface area of atleast 300 square meters/gram of silica having S-valule 10-60% | AKZO NOBEL NV (NL) | 2001-06-28 | — | — | US | claimed |
| EP-4291543-A1 | REACTION METHODS FOR PRODUCING NITROGENOUS PHOSPHORYL COMPOUNDS THAT ARE IN SITU FLUID COMPOSITIONS | Mcknight, Gary, David (US) | 2023-12-20 | — | — | EP | disclosed |
| US-20230140913-A1 | REACTION METHODS FOR PRODUCING NITROGENOUS PHOSPHORYL COMPOUNDS THAT ARE IN SITU FLUID COMPOSITIONS | SOILGENIC TECHNOLOGIES, LLC | 2023-05-11 | — | — | US | disclosed |
| WO-2022197751-A1 | REACTION METHODS FOR PRODUCING NITROGENOUS PHOSPHORYL COMPOUNDS THAT ARE IN SITU FLUID COMPOSITIONS | MCKNIGHT GARY DAVID (US) | 2022-09-22 | — | — | WO | disclosed |
| EP-2370394-A2 | FABRIC SOFTENING COMPOSITIONS AND METHODS | Colgate-Palmolive Company (US) | 2011-10-05 | — | — | EP | disclosed |
| US-20110229428-A1 | FABRIC SOFTENING COMPOSITIONS AND METHODS | COLGATE-PALMOLIVE COMPANY | 2011-09-22 | — | — | US | disclosed |
| WO-2010062924-A2 | FABRIC SOFTENING COMPOSITIONS AND METHODS | COLGATE-PALMOLIVE COMPANY (US) | 2010-06-03 | — | — | WO | disclosed |
| EP-1322167-B1 | ALLERGEN NEUTRALIZATION COMPOSITIONS | PROCTER & GAMBLE (US) | 2006-11-02 | — | — | EP | disclosed |
| US-6893538-B2 | Process for the production of paper using silica-based sols | AKZO NOBEL N.V. (NL) | 2005-05-17 | — | — | US | disclosed |
| EP-1363645-A1 | ALLERGEN NEUTRALIZATION COMPOSITIONS CONTAINING ALUMINUM IONS | THE PROCTER & GAMBLE COMPANY (US) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002028179-A1 | ALLERGEN NEUTRALIZATION COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2002-04-11 | — | — | WO | disclosed |
| WO-2002028187-A1 | ALLERGEN NEUTRALIZATION COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2002-04-11 | — | — | WO | disclosed |
| WO-2001046072-A1 | SILICA-BASED SOLS | AKZO NOBEL N.V. (NL) | 2001-06-28 | — | — | WO | disclosed |
| US-20010004927-A1 | Aqueous silica-based sol comprising a nitrogen-containing organic compound and silica-based particles with a specific surface area of atleast 300 square meters/gram of silica having S-valule 10-60% | AKZO NOBEL NV (NL) | 2001-06-28 | — | — | US | disclosed |
| US-6008178-A | LAUNDRY AND DISH WASHING CLEANER FOR REMOVING PROTEINACEOUS SOILS | PROCTER & GAMBLE COMPANY (US) | 1999-12-28 | — | — | US | disclosed |
| US-5684065-A | LASER BEAM | DAIKIN INDUSTRIES, LTD. (JP) | 1997-11-04 | — | — | US | disclosed |
| EP-0769517-A1 | SURFACE-MODIFIED FLUORORESIN MOLDED PRODUCT | DAIKIN INDUSTRIES, LTD. (JP) | 1997-04-23 | — | — | EP | disclosed |
| US-5391632-A | Paraffin inhibitors in crude oils and petroleum products | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-02-21 | — | — | US | disclosed |
| US-4605772-A | Process for preparing N-alkane-N-alkanolamines | THE DOW CHEMICAL COMPANY (US) | 1986-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110229428-A1 | FABRIC SOFTENING COMPOSITIONS AND METHODS | ASH2L, SMARCC2, ASH1L | CYP3A4 4334/4885SLC5A7 1523/4885TSHR 3990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.