Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28542901 | 0.83 | ALDH1A1 (0.65) | XDHALDH1A1TSHRKMT2ATP53 | |
| SCHEMBL28544806 | 0.82 | XDH (0.46) | XDHALDH1A1TSHRKMT2ALMNA | |
| SCHEMBL28544577 | 0.82 | XDH (0.46) | XDHALDH1A1TSHRKMT2ALMNA | |
| SCHEMBL28539223 | 0.81 | XDH (0.45) | XDHALDH1A1TSHRKMT2ALMNA | |
| SCHEMBL28552594 | 0.79 | ALDH1A1 (0.54) | XDHALDH1A1TSHRKMT2ALMNA | |
| SCHEMBL28552551 | 0.79 | XDH (0.58) | XDHALDH1A1TSHRKMT2A | |
| SCHEMBL28552545 | 0.79 | XDH (0.52) | XDHALDH1A1 | |
| SCHEMBL28554957 | 0.79 | XDH (0.52) | XDHALDH1A1 | |
| SCHEMBL28550909 | 0.78 | XDH (0.51) | XDH | |
| SCHEMBL4197409 | 0.77 | XDH (0.48) | XDHALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156769-B | Compound with xanthine oxidase inhibitory activity and preparation method and application thereof | 沈阳海诺威医药科技有限公司 | 2020-08-21 | — | — | CN | claimed |
| CN-110156757-B | Tetrazole type xanthine oxidase inhibitor compound and preparation method and application thereof | 沈阳海诺威医药科技有限公司 | 2021-04-16 | — | — | CN | disclosed |