Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 3/20 | 0.52 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28554957 | 0.89 | XDH (0.52) | XDHPTGER1KDM4EALDH1A1POLB | |
| SCHEMBL28552594 | 0.87 | ALDH1A1 (0.54) | XDHKDM4EALDH1A1HPGD | |
| SCHEMBL28542898 | 0.86 | XDH (0.45) | XDHMRGPRX4PTGER1KDM4EPOLB | |
| SCHEMBL28550909 | 0.86 | XDH (0.51) | XDH | |
| SCHEMBL28911861 | 0.82 | XDH (0.48) | XDHMRGPRX4ALDH1A1 | |
| SCHEMBL28545051 | 0.81 | XDH (0.58) | XDHMRGPRX4 | |
| SCHEMBL28556756 | 0.81 | XDH (0.58) | XDHCCR5MRGPRX4 | |
| SCHEMBL28553152 | 0.80 | XDH (0.56) | XDHMRGPRX4ALDH1A1 | |
| SCHEMBL28550907 | 0.79 | XDH (0.50) | XDHALDH1A1 | |
| SCHEMBL28544806 | 0.79 | XDH (0.46) | XDHKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156769-B | Compound with xanthine oxidase inhibitory activity and preparation method and application thereof | 沈阳海诺威医药科技有限公司 | 2020-08-21 | — | — | CN | claimed |
| CN-110156757-B | Tetrazole type xanthine oxidase inhibitor compound and preparation method and application thereof | 沈阳海诺威医药科技有限公司 | 2021-04-16 | — | — | CN | disclosed |