Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 3/20 | 0.47 |
| ▸ | BRD4 | O60885 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28546442 | 0.84 | S1PR4 (0.42) | S1PR4LMNATDP1SMN1; SMN2POLB | |
| SCHEMBL28912013 | 0.77 | CA12 (0.46) | BRD4LMNAMAPTMAPK1TSHR | |
| SCHEMBL28550968 | 0.76 | BRD4 (0.38) | BRD4LMNATDP1MAPT | |
| SCHEMBL3654191 | 0.76 | PDE7A (0.63) | S1PR4LMNATDP1SMN1; SMN2POLB | |
| SCHEMBL20855342 | 0.75 | S1PR4 (0.73) | S1PR4LMNATDP1SMN1; SMN2POLB | |
| SCHEMBL10489722 | 0.74 | LMNA (0.53) | S1PR4BRD4LMNATDP1SMN1; SMN2 | |
| SCHEMBL4965836 | 0.74 | MAPK1 (0.62) | S1PR4LMNATDP1SMN1; SMN2POLB | |
| SCHEMBL28541638 | 0.74 | HPGD (0.43) | LMNATDP1SMN1; SMN2POLBHPGD | |
| SCHEMBL10756271 | 0.73 | S1PR4 (0.56) | S1PR4LMNATDP1SMN1; SMN2POLB | |
| SCHEMBL16295426 | 0.70 | SLC6A2 (0.52) | S1PR4LMNATDP1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109574945-B | Isoxazoline derivatives and their use in agriculture | 东莞市东阳光农药研发有限公司 | 2021-04-20 | — | — | CN | disclosed |