Isophthalic Acid

Isophthalic Acid

SCHEMBL28550985

NS(=O)(=O)O.O=C(O)c1cccc(C(=O)O)c1.OCCCCCCO

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.49
CA1 P00915 5/20 0.48
CA2 P00918 5/20 0.48
CA9 Q16790 3/20 0.48
CA12 O43570 1/20 0.44
CA6 P23280 1/20 0.44
F2 P00734 2/20 0.44
PRSS1 P07477 2/20 0.44
PRSS2 P07478 2/20 0.44
PRSS3 P35030 2/20 0.44
FOLH1 Q04609 1/20 0.43
ANPEP P15144 1/20 0.42
ENPEP Q07075 1/20 0.42
KMO O15229 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.42
MAPK1 P28482 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isophthalic Acid SCHEMBL28537009 0.98 CYP2C19 (0.50) CYP2C19CA1CA2CA9CA12
Isophthalic Acid SCHEMBL3673276 0.89 CA12 (0.54) CYP2C19CA1CA2CA9CA12
Isophthalic Acid SCHEMBL28339168 0.87 CA1 (0.58) CYP2C19CA1CA2CA9CA12
Isophthalic Acid SCHEMBL4651781 0.87 CA12 (0.56) CYP2C19CA1CA2CA9CA12
Terephthalic Acid SCHEMBL28549034 0.85 CA2 (0.53) CYP2C19CA1CA2CA9CA12
Terephthalic Acid SCHEMBL6898217 0.85 TSHR (0.50) CYP2C19CA1CA2CA9CA12
Terephthalic Acid SCHEMBL28551334 0.83 CA2 (0.55) CYP2C19CA1CA2CA9CA12
Terephthalic Acid SCHEMBL5631843 0.83 TSHR (0.52) CYP2C19CA1CA2CA9CA12
Sulfamate SCHEMBL28550984 0.83 TDP1 (0.51) CA1CA2CA9CA12TDP1
1,6-Hexanediol SCHEMBL28215460 0.83 CYP4F2 (0.43) CYP2C19CA1CA2CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109734871-B Preparation method of polyurethane emulsion with low water absorption and high solid content 沈阳化工研究院有限公司 2021-04-13 CN disclosed