Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL5631843 | 0.98 | TSHR (0.52) | TSHRDAONAPRTCA12CA1 | |
| Isophthalic Acid SCHEMBL3673276 | 0.96 | CA12 (0.54) | TSHRDAONAPRTCA12CA1 | |
| Isophthalic Acid SCHEMBL4651781 | 0.94 | CA12 (0.56) | TSHRDAONAPRTCA12CA1 | |
| Terephthalic Acid SCHEMBL753918 | 0.90 | TSHR (0.56) | TSHRDAONAPRTCA12CA1 | |
| Terephthalic Acid SCHEMBL27677452 | 0.90 | TSHR (0.56) | TSHRDAONAPRTCA12CA1 | |
| Terephthalic Acid SCHEMBL6892927 | 0.89 | GPR84 (0.50) | TSHRDAONAPRTCA12CA1 | |
| Terephthalic Acid SCHEMBL10681045 | 0.88 | GPR84 (0.48) | TSHRDAONAPRTCA12CA1 | |
| Terephthalic Acid SCHEMBL6898525 | 0.88 | KMT2A (0.44) | TSHRDAONAPRTCA12CA1 | |
| Benzoic Acid SCHEMBL11896261 | 0.87 | TSHR (0.67) | TSHRDAONAPRTMEN1KMT2A | |
| Benzoic Acid SCHEMBL11896236 | 0.87 | TSHR (0.67) | TSHRDAONAPRTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6743741-B1 | Process for producing adhesive for fusion bonding, adhesive for fusion bonding obtained by the process, and adhesive fabric containing the adhesive for fusion bonding | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2004-06-01 | — | — | US | disclosed |
| EP-1231247-A1 | PROCESS FOR PRODUCING ADHESIVE FOR FUSION BONDING, ADHESIVE FOR FUSION BONDING OBTAINED BY THE PROCESS, AND ADHESIVE FABRIC CONTAINING THE ADHESIVE FOR FUSION BONDING | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |