SCHEMBL28551111

SCHEMBL28551111

CC(O)C(O)Nc1c(I)c(C(N)=O)c(I)c(C(=O)N(C(CO)CO)C(CO)CO)c1I

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7075563 0.82 LMNA (0.55) LMNA
SCHEMBL28451566 0.82 LMNA (0.55) LMNA
SCHEMBL29084760 0.77 LMNA (0.47) LMNA
SCHEMBL30397862 0.76
SCHEMBL7076147 0.75 LMNA (0.39) LMNA
SCHEMBL2537369 0.71
SCHEMBL9196446 0.69 LMNA (0.47) LMNA
SCHEMBL29084754 0.68 LMNA (0.39) LMNA
SCHEMBL9190900 0.67 LMNA (0.33) LMNA
SCHEMBL9000089 0.67 SMN1; SMN2 (0.39) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118324652-A Method for deiodination of X-CT iodine series contrast agent and intermediate benzene ring thereof 浙江海洲制药股份有限公司 2024-07-12 CN disclosed
CN-114605280-B Improved method for preparing iopamidol intermediate 安徽普利药业有限公司 2024-07-09 CN disclosed
CN-114656370-B Refining method of iopamidol intermediate 安徽普利药业有限公司 2024-06-18 CN disclosed
CN-115010617-B Preparation method of iopamidol 安徽普利药业有限公司 2024-06-11 CN disclosed
CN-115010617-A Preparation method of iopamidol 安徽普利药业有限公司 2022-09-06 CN disclosed
CN-114605280-A Improved method for preparing iopamidol intermediate 海南普利制药股份有限公司 2022-06-10 CN disclosed
CN-111272608-B Content determination method of stable nonionic iodine contrast agent 南京正大天晴制药有限公司 2021-04-02 CN disclosed
CN-111272608-A Content determination method of stable ionic iodine contrast agent 南京正大天晴制药有限公司 2020-06-12 CN disclosed